The University of Hawaii - Manoa appeared on H50 several times.
* Leonard Tokura's daughter stood before Hawaii Hall, an administration building, in "Samurai" (Season 1).
* It was where the dictator's daughter was kidnapped in "A Bullet for El Diablo" (Season 6).
* Kuykendall Hall represented the chemistry building in "Nine Dragons" (Season 9).
* An unknown building on campus represented a hospital in one episode and an Army research facility in another.